Research Associate - Discovery Pharmacology (FTC)
Matt Slinger
Based in Cambridge with nearly 80 employees, our client are a leading biotherapeutic company with a specialism within the Oncology field. They are expanding extensively at the moment, and are looking for applications for a number of positions within their research teams.

They are actively seeking applications for applicants for their Research Associate within the discovery pharmacology team. The position is initially on a 12-month FTC.

The successful applicant will have prior hands-on experience of assay development and screening in an industry setting. Direct experience of mammalian cell culture and development, optimisation and validation of cell-based technologies such as reporter gene assays and flow cytometry is highly desirable. You will enjoy a varied and rewarding role, developing and running a range of in vitro assays to screen and characterise novel peptides identified by the clients platform. You will be joining an established and expanding biology team, supporting multiple programs across a diverse range of therapeutic areas. You will be predominantly lab-based and responsible for generating key affinity, selectivity and mechanism of action data by running biochemical and cell-based, binding and functional assays with the aim of identifying and characterising high affinity peptides.

Key Responsibilities

+ Maintain mammalian cell cultures using aseptic technique, providing assay-ready cells to the wider team.
+ Use existing validated biochemical, biophysical and cell-based assays to characterize within a matrixed drug discovery team to agreed timelines
+ You will be expected to analyze and critically interpret assay data, to characterize the pharmacology and mechanism of action.
+ Problem-solve, troubleshoot and identify potential next steps, improvements and alternative/novel technologies
+ Record experiments accurately and diligently in electronic lab books and databases

Key Skills and Competencies

+ BSc in a relevant field plus prior experience from at least one role in a pharmaceutical or biotech setting
+ Previous experience in mammalian cell culture and performing cell-based binding and functional assays such as flow cytometry and signalling assays
+ Previous experience across a diverse array of assay platforms (e.g. SPR, fluorescence polarisation, HTRF, AlphaScreen) plus an interest in developing and implementing new technologies
+ Strong team-work and interpersonal skills.

Desirable Capabilities:

+ Experience with small molecule drug discovery projects and a robust understanding of the wider drug discovery process
+ Experience in using data analysis software packages, databases and ELNs e.g. Dotmatics and GraphPad Prism

If this role sounds interesting please contact Matt Slinger on 0161 923 8173.
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If you feel that you have the required experience for the position we would love to hear from you. Please send us a copy of your CV and we will be sure to consider you. If you would like to speak to us directly then please call on 0161 236 8200.

contact us

North Point Recruitment Ltd


1 City Approach

Albert Street


M30 0BG

0161 236 8200